Advanced Plant Pharmaceuticals, Inc. (APPI), New York, NY, has signed a marketing and distribution agreement with Tele-V, Inc., Hoofddorp, The Netherlands. According to the terms of the agreement, Tele-V has the exclusive right to purchase certain minimums by July 2003 of APPI’s patented cholesterol-re­ducing dietary supplement, Lo-Chol, for resale. In exchange for awarding Tele-V the exclusive rights for the marketing and distribution of Lo-Chol, Tele-V has agreed to bear all costs associated with the marketing, designs and distribution of Lo-Chol, including a significant commitment of media buys. Tele-V will produce and air a Lo-Chol radio commercial within 90 days of the agreement, followed by the production and airing of an infomercial on Lo-Chol within 120 days.